Fc Rγ Represents the Fc Receptor γ Chain Whereas FcγR Means the Fc Receptor for IgG

The Low Affinity Fc Receptor for IgG

High Affinity Receptor for IgG (Fc

The Human Cytomegalovirus Fc Receptor gp68 Binds the Fc CH2- CH3 Interface of IgG

Characterization of the IgG-Fc receptor on human platelets.

To determine quantitatively the number and avidity of receptors for the Fc portion of IgG on human platelets, we have measured the binding to platelets of human monomeric monoclonal IgG, and of small covalently crosslinked polymers of IgG1 labeled with 125I. The binding of labeled IgG1 monomers to platelets is too weak to permit quantitation. The binding of dimers or larger polymers of IgG1 is ...

Human Fc receptor-like 5 binds intact IgG via mechanisms distinct from those of Fc receptors.

Fc receptor-like (FCRL) 5 regulates B cell Ag receptor signaling and has been reported to bind aggregated IgG. Using surface plasmon resonance, we analyzed the interaction of native IgG samples with FCRL5, revealing a complex binding mechanism, where isotype is just one factor. FCRL5 bound IgG1 and IgG4 with ~1 μM KD, whereas the interaction with IgG3 was a magnitude weaker. However, IgG2 sampl...